William P. Timmie Professor of Psychiatry and Behavioral Sciences
Andrew H. Miller, M.D.
Andrew H. Miller, M.D.
Vice Chair of Research, Psychiatry and Behavioral Sciences
Director, Behavioral Immunology Program
co-Leader, Cancer Prevention and Control, Winship Cancer Institute
1997 Independent Investigator Grant
Dr. Miller is an internationally recognized leader in the area of brain-immune interactions as they relate to depression in medically healthy as well as medically ill patients including patients with cancer. His work has demonstrated that during immune activation, inflammatory cytokines can access the brain and interact with the metabolism of dopamine and glutamate, while altering neurocircuits in the brain relevant to motivation and reward as well as anxiety and alarm. Dr. Miller has also studied the impact of cytokines on neuroendocrine regulation and sleep including the study of the specific signal transduction pathways involved. Additionally, Dr. Miller and his group conducted the first clinical trial examining the efficacy of a cytokine antagonist for the treatment of depression, providing a template for current clinical trials using immunotherapeutic strategies to treat mood disorders. Learn more.
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The Brain & Behavior Research Foundation is a global nonprofit organization focused on improving the understanding, prevention and treatment of psychiatric and mental illnesses.
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