John L.R. Rubenstein, M.D., Ph.D.

John L.R. Rubenstein, M.D., Ph.D. - research expert on autism spectrum disorders
John L.R. Rubenstein, M.D., Ph.D.

Nina Ireland Distinguished Professor in Child Psychiatry

University of California at San Francisco

1997 Distinguished Investigator Grantee

1992, 1990 Young Investigator Grantee

2016 Ruane Prizewinner for Outstanding Achievement in Child and Adolescent Psychiatric Research

Joined the Foundation Scientific Council in 1998

Dr. Rubenstein’s genetic analyses of frontal lobe development led to identification of genes that are associated with Autism Spectrum Disorders. He has made major contributions to understanding fundamental mechanisms of forebrain development, including studies on forebrain organization, patterning centers, transcription factors that control regional specification of brain and craniofacial subdivisions, the linking of regional and cell type specification in the telencephalon, the demonstration that cortical inhibitory neurons are generated in the basal ganglia and tangentially migrate to the cortex, and the postnatal differentiation of cortical inhibitory neurons. His studies have implications on mechanisms underlying several developmental disorders, such as autism and epilepsy.

Prizewinner Video:


Symposium Presentation:

Genetic Analyses of Forebrain Development Give Insights into Origins of Neuropsychiatric Disorders
October 28, 2016, New York City

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