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How long will it take to get real improvements in treatment for illnesses like schizophrenia?

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Q. How long will it take to get real improvements in treatment for illnesses like schizophrenia?

Bryan L. Roth, M.D., Ph.D.
Answer By: Bryan L. Roth, M.D., Ph.D.
Michael J. Hooker Chair of Protein Therapeutics and Translational Proteomics, Distinguished Professor, Department of Pharmacology, School of Medicine, and Division of Medicinal Chemistry and Natural Products, School of Pharmacy
Director, National Institute of Mental Health (NIMH) Psychoactive Drug Screening Program
University of North Carolina Chapel Hill Medical School
There are several novel medications in both early- and later-stage clinical development which hold out hope for new treatment options as well as many in earlier stages of the pipeline. If only one of these proved effective (for example Gly-T I inhibitors currently in Phase III trials), we could expect new options within a couple of years. The early stage medications, coming mainly from pharmaceutical companies, are at least 5 years away. A new pan-NIH-initiative to accelerate drug discovery via academic labs could yield fruit, with a fair amount of luck, within the 5-year timeline.
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