Brain and Behavior Research Foundation

Identification of Genes Associated with Schizophrenia

identify genes that increase susceptibility for developing schizophrenia

Daniel Weinberger, M.D., received a NARSAD Distinguished Investigator Grant in 2000 to take an innovative approach in the search to identify genes that increase susceptibility for developing schizophrenia. Dr. Weinberger worked with 400 sibling pairs and measured levels of the brain chemical n-acetyl-aspartate (NAA), a neurochemical measure related to the integrity of glutamate neurons, to determine if this could be linked with targeted genetic association studies in schizophrenia.