Investigating Neurobiology and New Treatments for Addiction, Depression and Anxiety

Tuesday, February 8, 2022, 2:00 pm EST
Meet the Scientist - February 2022

Dr. Addy and his research team study the brain processes that contribute to addiction, depression, and anxiety. In this talk, Dr. Addy will discuss his research on calcium processes within the brain’s reward system, that may serve as effective therapeutic targets. He will also describe how current FDA approved medications, that impact these brain calcium processes, could be repurposed as novel, effective treatments for addiction, mood disorders, and co-occurring addiction, depression and/ or anxiety.

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Presented by 
Nii Addy, Ph.D.
Nii Addy, Ph.D.
Yale School of Medicine

Associate Professor of Psychiatry

Scientific Council Member (Joined 2020)

Dr. Addy’s research focuses on the neurobiology of motivational control, reward behavior, and reinforcement learning. He seeks to identify how these brain processes are altered in substance use disorders, depression and anxiety. Dr. Addy’s work incorporates various methods including the use of preclinical rodent models, electrochemistry, cellular and molecular biology, and electrophysiology. His lab has identified neurotransmitter mechanisms, namely dopamine and acetylcholine interactions, in specific brain pathways that regulate drug-relapse behavior and responses to stress and anxiety. His lab also examines neurotransmitter receptors and calcium channels that may serve as therapeutic targets to treat substance use and mood disorders. As part of the Yale Tobacco Center for Regulatory Science (TCORS), Dr. Addy’s team examines the effects of tobacco product flavors on nicotine reward and aversion, and on nicotine use behavior. In addition to basic science research, Dr.

Moderated by 
Jeffrey Borenstein, M.D.
Brain & Behavior Research Foundation

President and CEO

Jeffrey Borenstein, M.D., serves as the President & CEO of the Brain & Behavior Research Foundation, the largest private funder of mental health research grants. Dr. Borenstein developed the Emmy Award-nominated public television program “Healthy Minds,” and serves as host of the series. The program, which is broadcast nationwide, focuses on topics in psychiatry in order to educate the public, reduce stigma and offer a message of hope. Dr. Borenstein also serves as Editor-in-Chief of Psychiatric News, the newspaper of the American Psychiatric Association and as an Associate Clinical Professor of Psychiatry at Columbia University College of Physicians and Surgeons.