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Next-Generation Therapies

Next-Generation Therapies

We invest in next-generation therapies to reduce symptoms of mental illness and ultimately prevent and cure brain and behavior disorders.

Discovery Articles

A Medicine That Treats Mania Also Shows Effectiveness in Treating Depression in Bipolar Disorder

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Posted: Tuesday, March 19, 2019

A Medicine That Treats Mania Also Shows Effectiveness in Treating Depression in Bipolar Disorder

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Researchers Explore How Adolescent Chronic Cannabis Use Could Affect Adult Memory

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Posted: Tuesday, February 19, 2019

Researchers Explore How Adolescent Chronic Cannabis Use Could Affect Adult Memory

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Advisory Panel Recommends FDA Approval of Esketamine , with New Mechanism to Treat Resistant Depression & Suicidal Thinking

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Posted: Thursday, February 14, 2019

Advisory Panel Recommends FDA Approval of Esketamine, with New Mechanism to Treat Resistant Depression

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Adding Guanfacine Boosted Benefits of Cognitive Remediation Therapy in Schizophrenia Spectrum Disorder

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Posted: Wednesday, January 30, 2019

Adding Guanfacine Boosted Benefits of Cognitive Remediation Therapy in Schizophrenia Spectrum Disorder

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More Rapid Form of Brain Stimulation for Resistant Depression Worked as Well as Conventional TMS

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Posted: Monday, December 3, 2018

More Rapid Form of Brain Stimulation for Resistant Depression Worked as Well as Conventional TMS

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Seeking the Optimal Dose for Ketamine’s Short-Term Rapid Antidepressant Effects

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Posted: Tuesday, November 27, 2018

Seeking the Optimal Dose for Ketamine’s Short-Term Rapid Antidepressant Effects

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New Clues for Medication to Prevent Disorders Caused by Early-Life Stress

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Posted: Tuesday, November 13, 2018

New Clues for Medications to Prevent Disorders Caused by Early-Life Stress

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Computer-Delivered Cognitive Training Significantly Helped Schizophrenia Patients in Rehab Setting

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Posted: Monday, October 22, 2018

Computer-Delivered Cognitive Training Significantly Helped Schizophrenia Patients in Rehab Setting

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Immune System Factor Could Be Mobilized to Boost Motivation and Cognitive Deficits in Mental Illness

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Posted: Tuesday, October 9, 2018

Boosting Motivation and Cognitive Deficits in Mental Illness

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Researchers Discover That Fast-Acting Antidepressant Ketamine Engages the Body’s Opioid System

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Posted: Tuesday, October 2, 2018

Researchers Discover That Fast-Acting Antidepressant Ketamine Engages the Body’s Opioid System

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Intensive Outpatient Treatment Reduced Vets’ Symptoms of PTSD Within Weeks

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Posted: Monday, September 24, 2018

Intensive Outpatient Treatment Reduced Vets’ Symptoms of PTSD Within Weeks

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A Return To Life: One Patient’s Recovery After Receiving Deep Brain Stimulation For Depression

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Posted: Monday, September 17, 2018

A Return To Life: One Patient’s Recovery After Receiving Deep Brain Stimulation For Depression

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Ashwagandha, or Withania somnifera May Relieve Worsening Symptoms of Schizophrenia

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Posted: Wednesday, August 29, 2018

Medicinal Herb May Relieve Worsening Symptoms of Schizophrenia

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Folic Acid-Fortified Foods During Pregnancy May Support Child’s Brain Development After Birth

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Posted: Wednesday, July 25, 2018

Folic Acid-Fortified Foods During Pregnancy May Support Child’s Brain Development After Birth

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Parent-Child Therapy Reduced Depression Symptoms

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Posted: Wednesday, June 27, 2018

Interactive Parent-Child Therapy Reduced Depression Symptoms in Very Young Children

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Research Showing How Cocaine Addiction Reprograms the Brain Points to New Therapy Targets

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Posted: Tuesday, June 5, 2018

Research Showing How Cocaine Addiction Reprograms the Brain Points to New Therapy Targets

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Intensive PTSD Treatment

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Posted: Monday, May 7, 2018

Intensive PTSD Treatment Shows Success Among Post-9/11 Warriors

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Esketamine Reduced Suicidal Thoughts Within Hours of Treatment in Patients with Severe Depression

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Posted: Thursday, May 3, 2018

Esketamine Reduced Suicidal Thoughts Within Hours of Treatment in Patients with Severe Depression

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Posted: Wednesday, April 18, 2018

In Five-Year Study, Vagus Nerve Stimulation Added to Usual Care Improves Treatment-Resistant Depression Outcomes

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Molecular Picture Points the Way to Better Antipsychotic Medications

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Posted: Tuesday, March 20, 2018

Molecular Picture Points the Way to Better Antipsychotic Medications

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Relief from Decades of Treatment-Resistant Depression Comes with Metabolite Replacement Therapy Trial

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Posted: Tuesday, March 20, 2018

RESEARCH FOR RECOVERY: Relief from Decades of Treatment-Resistant Depression Comes with Metabolite Replacement Therapy Trial

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NAC Medication Improves Working Memory in Schizophrenia and Bipolar Patients with Psychosis

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Posted: Monday, March 12, 2018

NAC Medication Improves Working Memory in Schizophrenia and Bipolar Patients with Psychosis

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Two-coil Array for Transcranial Magnetic Stimulation

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Posted: Monday, March 5, 2018

Two-coil Array for Transcranial Magnetic Stimulation Appears Safe and Effective for Resistant Depression

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Brain Signature Predicts Who Benefits from Exposure Therapy

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Posted: Tuesday, February 20, 2018

Brain Signature Predicts Who Benefits from Exposure Therapy

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Strategy for Developing New Bipolar Disorder Treatments

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Posted: Tuesday, January 23, 2018

Animal Studies Suggest a Strategy for Developing New Bipolar Disorder Treatments

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Study Points to a New Class of Antidepressants

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Posted: Tuesday, December 12, 2017

Study Points to a New Class of Antidepressants

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New Analysis Finds Behavioral Therapy Should Be Combined with Medication to Relieve Severe Anxiety in Children

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Posted: Tuesday, November 14, 2017

New Analysis Finds Behavioral Therapy Should Be Combined with Medication to Relieve Severe Anxiety in Children

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Midday Light Therapy

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Posted: Monday, October 16, 2017

Study Shows Exposure to Bright Light at Midday Reduces Depression in Patients with Bipolar Disorder

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Ketamine Rapidly Reduced Suicidal Thoughts in People with Depression

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Posted: Tuesday, October 10, 2017

Ketamine Rapidly Reduced Suicidal Thoughts in People with Depression

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Benefits of Bringing Therapy to the Pediatrician’s Office

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Posted: Monday, October 2, 2017

Benefits of Bringing Therapy to the Pediatrician’s Office

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Lithium Reduces Mania in Bipolar Disorder Opens Research Path to More Effective Treatments

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Posted: Thursday, September 7, 2017

New Knowledge about How Lithium Reduces Mania in Bipolar Disorder Opens Research Path to More Effective Treatments

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Muscle Relaxant May Help in Treating Some Aspects of Alcohol Dependence in Anxious People

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Posted: Tuesday, August 15, 2017

Muscle Relaxant May Help in Treating Some Aspects of Alcohol Dependence in Anxious People

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