Next-Generation Therapies

Discovery Articles

Combined Psychosocial Treatment Helped Schizophrenia Patients with Motivational Negative Symptoms

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Posted: Thursday, September 21, 2023

Combined Psychosocial Treatment Helped Schizophrenia Patients with Motivational Negative Symptoms

In Schizophrenia, Reducing the Impact of Medications on One Neurotransmitter System Could Yield Gains in Cognition

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Posted: Tuesday, September 5, 2023

In Schizophrenia, Reducing the Impact of Medications on One Neurotransmitter System Could Yield Gains in Cognition

Nitrous Oxide (“Laughing Gas”) May Have Rapid-Acting Anti-Suicidal Effects

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Posted: Thursday, August 31, 2023

Nitrous Oxide (“Laughing Gas”) May Have Rapid-Acting Anti-Suicidal Effects

Rapid-Acting Pill to Treat Postpartum Depression is Approved

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Posted: Thursday, August 17, 2023

Rapid-Acting Pill to Treat Postpartum Depression is Approved

Two Forms of Non-Drug Therapy Helped Reduce Impulsive Aggression in Schizophrenia

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Posted: Thursday, July 27, 2023

Two Forms of Non-Drug Therapy Helped Reduce Impulsive Aggression in Schizophrenia

When Mothers Got CBT for Postpartum Depression, Emotion Regulation in Their Infants Improved

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Posted: Thursday, July 20, 2023

When Mothers Got CBT for Postpartum Depression, Emotion Regulation in Their Infants Improved

Study Examines Potential Resilience to Substance Use Disorder Following Childhood Maltreatment

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Posted: Thursday, July 13, 2023

Study Examines Potential Resilience to Substance Use Disorder Following Childhood Maltreatment

Trial Finds Ketamine and ECT About Equally Effective for Most Patients with Resistant Major Depression

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Posted: Thursday, June 8, 2023

Trial Finds Ketamine and ECT About Equally Effective for Most Patients with Resistant Major Depression

Rapid-Acting Brain Stimulation Method May Reduce Major Depression by Reversing Information Flow Between Brain Regions

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Posted: Thursday, May 25, 2023

Rapid-Acting Brain Stimulation Method May Reduce Major Depression by Reversing Information Flow Between Brain Regions

In Search of New Therapies, Studying the Neurobiology of Brain Development in Pediatric Anxiety

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Posted: Thursday, April 6, 2023

In Search of New Therapies, Studying the Neurobiology of Brain Development in Pediatric Anxiety

Study Indicates How rTMS Treatments Alter Neural Connectivity Brain-Wide in Treatment-Resistant Depressed Patients, a Clue to Predict Who Will Benefit

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Posted: Thursday, March 16, 2023

Study Indicates How rTMS Treatments Alter Neural Connectivity Brain-Wide in Treatment-Resistant Depressed Patients, a Clue to Predict Who Will Benefit

Pregnant Mice on High-Fat Diets Have Gut Microbe Deficiencies That Perturb Social Behavior Across Generations of Offspring, Study Finds

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Posted: Thursday, March 9, 2023

Pregnant Mice on High-Fat Diets Have Gut Microbe Deficiencies That Perturb Social Behavior Across Generations of Offspring, Study Finds

Study of How Schizophrenia Symptoms Affect One Another Finds Anhedonia and Low Motivation to Be Plausible Targets of Focused Treatments

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Posted: Thursday, February 23, 2023

Study of How Schizophrenia Symptoms Affect One Another Finds Anhedonia and Low Motivation to Be Plausible Targets of Focused Treatments

Talk Therapy + Brain Stimulation Reduced Suicidal Ideation in Patients with Borderline Personality Disorder and Treatment-Resistant Depression, Pilot Trial Shows

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Posted: Thursday, February 9, 2023

Talk Therapy + Brain Stimulation Reduced Suicidal Ideation in Patients with Borderline Personality Disorder and Treatment-Resistant Depression, Pilot Trial Shows

Brain Network Analysis Reveals a Depression – Multiple Sclerosis Connection

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Posted: Thursday, February 2, 2023

Brain Network Analysis Reveals a Depression – Multiple Sclerosis Connection

Home-Based tDCS Brain Stimulation Treatments Reduced Inattention in Adults with ADHD

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Posted: Thursday, December 8, 2022

Home-Based tDCS Brain Stimulation Treatments Reduced Inattention in Adults with ADHD

Video Game-Based Intervention Helped Reduce Cognitive Deficits in Depressed Patients

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Posted: Thursday, November 17, 2022

Video Game-Based Intervention Helped Reduce Cognitive Deficits in Depressed Patients

Clinical Trial Compared Different Forms of Exposure and Drug Therapy in Combat Veterans with PTSD

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Posted: Thursday, November 10, 2022

Clinical Trial Compared Different Forms of Exposure and Drug Therapy in Combat Veterans with PTSD

Adding an Antibiotic Improved Brain Stimulation Results in Depression

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Posted: Thursday, November 3, 2022

Adding an Antibiotic Improved Brain Stimulation Results in Depression

After ‘Priming’ with Ketamine, Patients Receiving Self-Esteem Training Had Extended Antidepressant Benefits, Study Finds

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Posted: Thursday, October 20, 2022

After ‘Priming’ with Ketamine, Patients Receiving Self-Esteem Training Had Extended Antidepressant Benefits, Study Finds

Folic Acid Supplements Were Associated With Lower Suicidality in Large Database Study

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Posted: Thursday, October 13, 2022

Folic Acid Supplements Were Associated With Lower Suicidality in Large Database Study

Two Forms of Non-Invasive Brain Stimulation Helped Older Adults with Treatment-Resistant Depression

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Posted: Thursday, October 6, 2022

Two Forms of Non-Invasive Brain Stimulation Helped Older Adults with Treatment-Resistant Depression

FDA Clears SAINT Rapid-Acting Brain Stimulation Approach for Those Suffering From Resistant Major Depression

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Posted: Thursday, September 15, 2022

FDA Clears SAINT Rapid-Acting Brain Stimulation Approach for Those Suffering From Resistant Major Depression

The last decade has seen a vast increase in the use of brain stimulation technologies to reduce symptoms of psychiatric illness. By far the most influential has been TMS, a non-invasive method employing magnets that generate electric fields which are thought to therapeutically alter the activity of neurons and brain circuits involved in depression and other disorders. TMS was pioneered by BBRF Scientific Council member Mark S. George, M.D., who used two early-career BBRF grants to develop the protocol ul

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Posted: Thursday, August 25, 2022

Team Assesses Safety of t-PBM, Non-Invasive Brain Stimulation Technology That Uses Light to Treat Depression and Anxiety

Comprehensive Analysis Suggests Metacognitive Training Can Be Effective in Schizophrenia and Psychotic Disorders

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Posted: Wednesday, July 20, 2022

Comprehensive Analysis Suggests Metacognitive Training Can Be Effective in Schizophrenia and Psychotic Disorders

1-Day Online CBT-Based Workshop Helped New Moms With Postpartum Depression

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Posted: Tuesday, July 12, 2022

1-Day Online CBT-Based Workshop Helped New Moms With Postpartum Depression

Some OCD Patients Who Attain “Wellness” After Exposure Therapy May Safely Taper Off Their SRI Medicines, Study Suggests

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Posted: Thursday, July 7, 2022

Some OCD Patients Who Attain “Wellness” After Exposure Therapy May Safely Taper Off Their SRI Medicines, Study Suggests

A Circuit Causally Linked With Spontaneous Nicotine Addiction Remissions May Be a Powerful Addiction Treatment Target

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Posted: Thursday, June 30, 2022

A Circuit Causally Linked With Spontaneous Nicotine Addiction Remissions May Be a Powerful Addiction Treatment Target

Researchers Discover Potentially Targetable Brain Circuit Controlling Cocaine Withdrawal Anxiety and Relapse

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Posted: Thursday, June 16, 2022

Researchers Discover Potentially Targetable Brain Circuit Controlling Cocaine Withdrawal Anxiety and Relapse

Combining Antidepressants Can Improve Outcomes in Patients with Severe Depression, Study Finds

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Posted: Thursday, June 9, 2022

Combining Antidepressants Can Improve Outcomes in Patients with Severe Depression, Study Finds

A Molecule Tested in Higher Primates Reduced Alcohol Consumption By Half

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Posted: Thursday, May 26, 2022

A Molecule Tested in Higher Primates Reduced Alcohol Consumption By Half

Stem Cell Technology Helps Identify a Potential Causal Mechanism in Schizophrenia That Could Be Targeted

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Posted: Thursday, May 5, 2022

Stem Cell Technology Helps Identify a Potential Causal Mechanism in Schizophrenia That Could Be Targeted

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Next-Generation Therapies