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Next-Generation Therapies

Next-Generation Therapies

We invest in next-generation therapies to reduce symptoms of mental illness and ultimately prevent and cure brain and behavior disorders.

Discovery Articles

Deep-Brain Stimulation Showed Multi-Year Effectiveness in Severely Depressed, Treatment-Resistant Patients

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Posted: Thursday, October 17, 2019

Deep-Brain Stimulation Showed Multi-Year Effectiveness in Severely Depressed, Treatment-Resistant Patients

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Fatty Acid Levels in the Brain Are Found to Correlate With Serotonin Transport and Depression Severity

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Posted: Thursday, October 10, 2019

Fatty Acid Levels in the Brain Are Found to Correlate With Serotonin Transport and Depression Severity

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Potential Biomarker May Predict Which Depressed Patients Getting CBT Will Have Added Benefit from tDCS Brain Stimulation

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Posted: Thursday, September 26, 2019

Potential Biomarker May Predict Which Depressed Patients Getting CBT Will Have Added Benefit from tDCS Brain Stimulation

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Non-Invasive Brain Stimulation May Help Some OCD Patients Who Don’t Respond to Medications or Psychotherapy

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Posted: Thursday, September 12, 2019

Non-Invasive Brain Stimulation May Help Some OCD Patients Who Don’t Respond to Medications or Psychotherapy

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Large Genome Study Suggests Anorexia Nervosa is a Metabolic Disorder as Well as a Psychiatric One

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Posted: Thursday, August 22, 2019

Large Genome Study Suggests Anorexia Nervosa is a Metabolic Disorder as Well as a Psychiatric One

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Study Finds Lithium Has Advantages Over Other Mood Stabilizers in Youths with Bipolar Disorder

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Posted: Thursday, August 15, 2019

Study Finds Lithium Has Advantages Over Other Mood Stabilizers in Youths with Bipolar Disorder

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RESEARCH FOR RECOVERY: Advances in Cognitive Remediation: ‘Helping Schizophrenia Patients Who Need It Most’

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Posted: Sunday, June 30, 2019

RESEARCH FOR RECOVERY: Advances in Cognitive Remediation: ‘Helping Schizophrenia Patients Who Need It Most’

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FDA Approves Cariprazine for Depression in Bipolar I Disorder

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Posted: Thursday, June 20, 2019

FDA Approves Cariprazine for Depression in Bipolar I Disorder

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Early-Morning Bright-Light Therapy Helped Patients with PTSD Symptoms

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Posted: Wednesday, May 8, 2019

Early-Morning Bright-Light Therapy Helped Patients with PTSD Symptoms

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Study: Ketamine Restores Neural Connection Points Lost in Stress & Depression

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Posted: Thursday, May 2, 2019

Study: Ketamine Restores Neural Connection Points Lost in Stress & Depression

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Different Response Patterns to TMS Therapy Treatment for Major Depression Point to Possibility of Individualized Treatments

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Posted: Thursday, April 25, 2019

Different Response Patterns to TMS Treatment for Major Depression Point to Possibility of Individualized Treatments

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In a Comparison of Two Kinds of Cognitive Training, One Appeared to Help Schizophrenia Patients More

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Posted: Tuesday, April 9, 2019

In a Comparison of Two Kinds of Cognitive Training, One Appeared to Help Schizophrenia Patients More

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Opioids, at Very Low Doses, May Provide a New Way to Treat Resistant Depression

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Posted: Sunday, March 31, 2019

Opioids, at Very Low Doses, May Provide a New Way to Treat Resistant Depression

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Pioneering TMS Therapy for Depression

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Posted: Sunday, March 31, 2019

Pioneering TMS Therapy for Depression

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What Is TMS Treatment and How Well does It Work?

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Posted: Sunday, March 31, 2019

What Is TMS Treatment and How Well does It Work?

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The First Drug Treatment To Specifically Relieve Postpartum Depression Is Approved

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Posted: Tuesday, March 26, 2019

The First Drug Treatment To Specifically Relieve Postpartum Depression Is Approved

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A Medicine That Treats Mania Also Shows Effectiveness in Treating Depression in Bipolar Disorder

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Posted: Tuesday, March 19, 2019

A Medicine That Treats Mania Also Shows Effectiveness in Treating Depression in Bipolar Disorder

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Researchers Explore How Adolescent Chronic Cannabis Use Could Affect Adult Memory

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Posted: Tuesday, February 19, 2019

Researchers Explore How Adolescent Chronic Cannabis Use Could Affect Adult Memory

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Advisory Panel Recommends FDA Approval of Esketamine , with New Mechanism to Treat Resistant Depression & Suicidal Thinking

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Posted: Thursday, February 14, 2019

Advisory Panel Recommends FDA Approval of Esketamine, with New Mechanism to Treat Resistant Depression

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Adding Guanfacine Boosted Benefits of Cognitive Remediation Therapy in Schizophrenia Spectrum Disorder

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Posted: Wednesday, January 30, 2019

Adding Guanfacine Boosted Benefits of Cognitive Remediation Therapy in Schizophrenia Spectrum Disorder

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More Rapid Form of Brain Stimulation for Resistant Depression Worked as Well as Conventional TMS

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Posted: Monday, December 3, 2018

More Rapid Form of Brain Stimulation for Resistant Depression Worked as Well as Conventional TMS

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Seeking the Optimal Dose for Ketamine’s Short-Term Rapid Antidepressant Effects

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Posted: Tuesday, November 27, 2018

Seeking the Optimal Dose for Ketamine’s Short-Term Rapid Antidepressant Effects

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New Clues for Medication to Prevent Disorders Caused by Early-Life Stress

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Posted: Tuesday, November 13, 2018

New Clues for Medications to Prevent Disorders Caused by Early-Life Stress

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Computer-Delivered Cognitive Training Significantly Helped Schizophrenia Patients in Rehab Setting

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Posted: Monday, October 22, 2018

Computer-Delivered Cognitive Training Significantly Helped Schizophrenia Patients in Rehab Setting

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Immune System Factor Could Be Mobilized to Boost Motivation and Cognitive Deficits in Mental Illness

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Posted: Tuesday, October 9, 2018

Boosting Motivation and Cognitive Deficits in Mental Illness

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Researchers Discover That Fast-Acting Antidepressant Ketamine Engages the Body’s Opioid System

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Posted: Tuesday, October 2, 2018

Researchers Discover That Fast-Acting Antidepressant Ketamine Engages the Body’s Opioid System

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Intensive Outpatient Treatment Reduced Vets’ Symptoms of PTSD Within Weeks

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Posted: Monday, September 24, 2018

Intensive Outpatient Treatment Reduced Vets’ Symptoms of PTSD Within Weeks

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A Return To Life: One Patient’s Recovery After Receiving Deep Brain Stimulation For Depression

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Posted: Monday, September 17, 2018

A Return To Life: One Patient’s Recovery After Receiving Deep Brain Stimulation For Depression

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Ashwagandha, or Withania somnifera May Relieve Worsening Symptoms of Schizophrenia

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Posted: Wednesday, August 29, 2018

Medicinal Herb May Relieve Worsening Symptoms of Schizophrenia

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Folic Acid-Fortified Foods During Pregnancy May Support Child’s Brain Development After Birth

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Posted: Wednesday, July 25, 2018

Folic Acid-Fortified Foods During Pregnancy May Support Child’s Brain Development After Birth

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Parent-Child Therapy Reduced Depression Symptoms

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Posted: Wednesday, June 27, 2018

Interactive Parent-Child Therapy Reduced Depression Symptoms in Very Young Children

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Research Showing How Cocaine Addiction Reprograms the Brain Points to New Therapy Targets

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Posted: Tuesday, June 5, 2018

Research Showing How Cocaine Addiction Reprograms the Brain Points to New Therapy Targets

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