Close menu
Brain & Behavior
Grants & Prizes
Home
Research
Illness
Addiction
Anxiety Disorders
Attention-Deficit Hyperactivity Disorder (ADHD)
Autism Spectrum Disorder (ASD)
Bipolar Disorder
Borderline Personality Disorder (BPD)
Depression
Eating Disorders
Mental Illness (General)
Obsessive-Compulsive Disorder (OCD)
Post-Traumatic Stress Disorder (PTSD)
Schizophrenia
Suicide Prevention
Other Brain-Related Illnesses
Category
Basic Research
New Technologies
Early Intervention/ Diagnostic Tools
Next Generation Therapies
Blog
Get Involved
Give
Donate Today
Memorial/Tribute (make donation)
Create Event or Memorial Page
Find a Memorial/Tribute Page
Stock/Securities Donations / IRA Charitable Rollovers
Other Giving Opportunities
Planned Giving
Research Partners
Donor Advised Funds
Workplace Giving
Team Up for Research!
Sponsorship Opportunities
Watch
Healthy Minds TV
Meet the Scientists Webinars
Videos
Connect
Ask the Expert
Join Us
Home
Grants
Grant FAQs
BBRF Young Investigator Grants
BBRF Independent Investigator Grants
BBRF Distinguished Investigator Grants
Prizes & Awards
Klerman & Freedman Prizes
Outstanding Achievement Prizes
Lieber Prize for Schizophrenia Research
Maltz Prize for Schizophrenia Research
Colvin Prize for Mood Disorders Research
Ruane Prize for Child and Adolescent Psychiatric Research
Goldman-Rakic Prize for Cognitive Neuroscience Research
The Pardes Humanitarian Prize
Productive Lives Awards
Blog
About Us
Who We Are
Our Impact
FAQs
Media Center
News
Press Releases
Opinion Pieces
In the News
Multimedia Library
Media Kit
Events & Webinars
Team Up for Research! Events
Healthy Minds TV
Contact
Email Signup
Open Menu

Menu

Depression

Depression

$89M Awarded to Depression Research since 1987

Learn About Depression

The Latest Research Discoveries

Team Reports on Search for Genetic Subgroups Within Depression

READ

Posted: Thursday, December 3, 2020

Team Reports on Search for Genetic Subgroups Within Depression

Read more
Study Reveals Adults With Mental Disorders Are At Significantly Higher Risk of COVID-19 and Have Poorer Outcomes

READ

Posted: Thursday, November 12, 2020

Study Reveals Adults With Mental Disorders Are At Significantly Higher Risk of COVID-19 and Have Poorer Outcomes

Read more
Researchers Discover a Role for Immune Cells Called Microglia in Inhibiting Brain Activity and Regulating Behavior

READ

Posted: Thursday, October 29, 2020

Researchers Discover a Role for Immune Cells Called Microglia in Inhibiting Brain Activity and Regulating Behavior

Read more
Study of Seniors With Depression Shows How They Are Dealing With the COVID-19 Pandemic

READ

Posted: Thursday, October 15, 2020

Study of Seniors With Depression Shows How They Are Dealing With the COVID-19 Pandemic

Read more
Team Discovers Mechanism in Blood-Vessel Cells in the Brain That Promotes Resilience Against Stress

READ

Posted: Thursday, September 24, 2020

Team Discovers Mechanism in Blood-Vessel Cells in the Brain That Promotes Resilience Against Stress

Read more
Large Genetic Study Expands Links Between DNA Variations and Problematic Drinking

READ

Posted: Thursday, September 17, 2020

Large Genetic Study Expands Links Between DNA Variations and Problematic Drinking

Read more
Magnetic Seizure Therapy (MST) Shows Promise as Possible Alternative to ECT for Reducing Major Depression and Suicidality

READ

Posted: Thursday, August 27, 2020

Magnetic Seizure Therapy (MST) Shows Promise as Possible Alternative to ECT for Reducing Major Depression and Suicidality

Read more
How the Brain’s Reward System Goes Awry in Depression Affecting Young People

READ

Posted: Thursday, August 13, 2020

How the Brain’s Reward System Goes Awry in Depression Affecting Young People

Read more
Remarkable Results in a Preliminary Clinical Test of a Rapid-Acting Antidepressant Treatment

READ

Posted: Tuesday, August 11, 2020

Remarkable Results in a Preliminary Clinical Test of a Rapid-Acting Antidepressant Treatment

Read more
New Insights About How Alcohol Withdrawal Changes the Brain Differently in Males and Females

READ

Posted: Thursday, June 25, 2020

New Insights About How Alcohol Withdrawal Changes the Brain Differently in Males and Females

Read more
Remarkable Improvement Rate Reported in Patients Who Received SAINT, an Experimental Non-Invasive Brain-Stimulation Treatment for Resistant Depression

READ

Posted: Thursday, June 18, 2020

Remarkable Improvement Rate Reported in Patients Who Received SAINT, an Experimental Non-Invasive Brain-Stimulation Treatment for Resistant Depression

Read more
Brain-wave EEG Signature Robustly Predicted Antidepressant Response

READ

Posted: Thursday, June 11, 2020

Brain-wave EEG Signature Robustly Predicted Antidepressant Response

Read more
In a Surprising Clinical Trial, Ketamine’s Antidepressant Effects Lasted Longer

READ

Posted: Thursday, May 14, 2020

In a Surprising Clinical Trial, Ketamine’s Antidepressant Effects Lasted Longer

Read more
https://www.bbrfoundation.org/sites/default/files/field/image/sadworriedyoungwoman-2-1440.jpg

READ

Posted: Thursday, April 30, 2020

Brain Activity While Anticipating a Working-Memory Task Could Help Distinguish Depression in Bipolar Disorder from Major Depression

Read more
Study of Loneliness in a Senior Housing Community Points to Risk and Potential Protective Factors

READ

Posted: Thursday, April 2, 2020

Study of Loneliness in a Senior Housing Community Points to Risk and Potential Protective Factors

Read more
Adding Ambien to an SSRI Antidepressant Could Help Some Depressed Patients with Severe Insomnia

READ

Posted: Thursday, March 19, 2020

Adding Ambien to an SSRI Antidepressant Could Help Some Depressed Patients with Severe Insomnia

Read more
Problems in Early Life Leave Biological Traces in Depressed Moms That May Impair Bonding With Their Babies

READ

Posted: Friday, March 13, 2020

Problems in Early Life Leave Biological Traces in Depressed Moms That May Impair Bonding With Their Babies

Read more
Activating Specific Serotonin Neurons Reduced Anxiety and Promoted Sleep in Mice

READ

Posted: Thursday, March 5, 2020

Activating Specific Serotonin Neurons Reduced Anxiety and Promoted Sleep in Mice

Read more
Impact of Electronic Media Use on Mental Health in Children

READ

Posted: Thursday, February 27, 2020

Study Finds “Small But Significant” Impact of Electronic Media Use on Mental Health in Children

Read more
Impact of Mother’s Depressive Symptoms Just Before and After Childbirth Upon Child’s Brain Development

READ

Posted: Thursday, January 30, 2020

Impact of Mother’s Depressive Symptoms Just Before and After Childbirth Upon Child’s Brain Development

Read more
Study Links Brain Connectivity Patterns with Response to Specific Antidepressant and Placebo

READ

Posted: Thursday, January 23, 2020

Study Links Brain Connectivity Patterns with Response to Specific Antidepressant and Placebo

Read more
Over Two Decades, 90 BBRF Grants Helped Build a Scientific Foundation for the First Rapid-Acting Antidepressants

READ

Posted: Tuesday, December 31, 2019

Over Two Decades, 90 BBRF Grants Helped Build a Scientific Foundation for the First Rapid-Acting Antidepressants

Read more
60 year study finds children of mothers who contracted bacterial infection during pregnancy have higher risk of psychosis

READ

Posted: Thursday, November 14, 2019

After 60 Years, Study Finds Children of Mothers with Bacterial Infections During Pregnancy Have Elevated Psychosis Risk

Read more
Deep-Brain Stimulation Showed Multi-Year Effectiveness in Severely Depressed, Treatment-Resistant Patients

READ

Posted: Thursday, October 17, 2019

Deep-Brain Stimulation Showed Multi-Year Effectiveness in Severely Depressed, Treatment-Resistant Patients

Read more
Fatty Acid Levels in the Brain Are Found to Correlate With Serotonin Transport and Depression Severity

READ

Posted: Thursday, October 10, 2019

Fatty Acid Levels in the Brain Are Found to Correlate With Serotonin Transport and Depression Severity

Read more
Potential Biomarker May Predict Which Depressed Patients Getting CBT Will Have Added Benefit from tDCS Brain Stimulation

READ

Posted: Thursday, September 26, 2019

Potential Biomarker May Predict Which Depressed Patients Getting CBT Will Have Added Benefit from tDCS Brain Stimulation

Read more
Non-Invasive Brain Stimulation May Help Some OCD Patients Who Don’t Respond to Medications or Psychotherapy

READ

Posted: Thursday, September 12, 2019

Non-Invasive Brain Stimulation May Help Some OCD Patients Who Don’t Respond to Medications or Psychotherapy

Read more
Researchers Propose a Way to Study the Debilitating Symptoms of Borderline Personality Disorder

READ

Posted: Thursday, September 5, 2019

Researchers Propose a Way to Study the Underlying Causes of Borderline Personality Disorder

Read more
Early Reductions in Irritability Are Found to Predict Treatment Results in Some Patients with Major Depression

READ

Posted: Tuesday, July 16, 2019

Early Reductions in Irritability Are Found to Predict Treatment Results in Some Patients with Major Depression

Read more
Brain Scans Reveal a Possible Biomarker for Suicidal Thoughts in PTSD

READ

Posted: Thursday, May 16, 2019

Brain Scans Reveal a Possible Biomarker for Suicidal Thoughts in PTSD

Read more
Early-Morning Bright-Light Therapy Helped Patients with PTSD Symptoms

READ

Posted: Wednesday, May 8, 2019

Early-Morning Bright-Light Therapy Helped Patients with PTSD Symptoms

Read more
Study: Ketamine Restores Neural Connection Points Lost in Stress & Depression

READ

Posted: Thursday, May 2, 2019

Study: Ketamine Restores Neural Connection Points Lost in Stress & Depression

Read more
More Articles

Key Figures

300 million

Globally, an estimated 300 million people of all ages suffer from depression.*

* Source: World Health Organization (WHO)

15.7 million adults

In 2014, around 15.7 million adults age 18 or older in the U.S. had experienced at least one major depressive episode in the last year (6.7% of adults in the U.S.).*

* Source: National Institute of Mental Health

2 out of 100

As many as 2 out of 100 young children and 8 out of 100 teens may have serious depression.*

* Source: Anxiety and Depression Association of America (ADAA)

Featured Tweet

A new, more rapid form of transcranial magnetic stimulation holds promise for treating #depression. TWEET

Meet a Researcher

Kirsten A. Donald, M.D.
Read Full Bio
Kirsten A. Donald, M.D.

Associate Professor

University of Cape Town, South Africa

2016 Independent Investigator Grant

Ask an Expert

Huda Akil, Ph.D. - Brain & behavior research expert on depression
Read the answer
Huda Akil, Ph.D.

Gardner Quarton Distinguished University Professor of Neuroscience and Psychiatry

Co-Director, Molecular and Behavioral Neuroscience Institute

University of Michigan

2007 Goldman-Rakic Prize for Outstanding Achievement in Cognitive Neuroscience

Question:

In your work with the Pritzker Neuropsychiatric Research Consortium, have you uncovered any new genes that you think might be related to mental illnesses besides major depression?

News and Events