Research

Brain and Behavior Research Foundation

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1 in 5 of Us Lives With a Mental Illness

Addiction

$11M Awarded to Addiction Research since 1987

Attention-Deficit Hyperactivity Disorder (ADHD)

$5M Awarded to ADHD Research since 1987

Anxiety

$13.5M Awarded to Anxiety Disorders Research since 1987

Autism

$17M Awarded to Autism Research since 1987

Bipolar Disorder

$32M Awarded to Bipolar Disorder Research since 1987

Borderline Personality Disorder

$1M Awarded to BPD Research since 1987

Depression

$99M Awarded to Depression Research since 1987

Eating Disorders

$3.7M Awarded to Eating Disorders Research since 1987

Obsessive-Compulsive Disorder (OCD)

$5M Awarded to OCD Research since 1987

Post-Traumatic Stress Disorder (PTSD)

$12M Awarded to PTSD Research since 1987

Schizophrenia

$159M Awarded to Schizophrenia Research since 1987

Mental Illness (General)

$69M Awarded to Other Brain-Related Illnesses or Projects Covering Multiple Illnesses

Grants are awarded three times/year. Total dollars awarded are updated annually.

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Research Categories

Basic Research

We invest in basic research to understand what happens in the brain to cause mental illness.

New Technologies

We invest in new technologies to advance or create new ways of studying and understanding the brain.

Diagnostic Tools / Early Intervention

We invest in diagnostic tools and early intervention research to recognize early signs of mental illness and begin treatment as early as possible.

Next-Generation Therapies

We invest in next-generation therapies to reduce symptoms of mental illness and ultimately prevent and cure brain and behavior disorders.

Research Articles

Important New Research on Schizophrenia Genetics Provides Strongest Evidence to Date of Problems at the Brain’s Synapses

READ

Posted: Thursday, December 1, 2022

Important New Research on Schizophrenia Genetics Provides Strongest Evidence to Date of Problems at the Brain’s Synapses

Video Game-Based Intervention Helped Reduce Cognitive Deficits in Depressed Patients

READ

Posted: Thursday, November 17, 2022

Video Game-Based Intervention Helped Reduce Cognitive Deficits in Depressed Patients

Clinical Trial Compared Different Forms of Exposure and Drug Therapy in Combat Veterans with PTSD

READ

Posted: Thursday, November 10, 2022

Clinical Trial Compared Different Forms of Exposure and Drug Therapy in Combat Veterans with PTSD

Adding an Antibiotic Improved Brain Stimulation Results in Depression

READ

Posted: Thursday, November 3, 2022

Adding an Antibiotic Improved Brain Stimulation Results in Depression

Lab-Grown Human Neurons Transplanted into the Rat Brain Grew, Connected, and Promise to Shed Light on Psychiatric Illness

READ

Posted: Thursday, October 27, 2022

Lab-Grown Human Neurons Transplanted into the Rat Brain Grew, Connected, and Promise to Shed Light on Psychiatric Illness

After ‘Priming’ with Ketamine, Patients Receiving Self-Esteem Training Had Extended Antidepressant Benefits, Study Finds

READ

Posted: Thursday, October 20, 2022

After ‘Priming’ with Ketamine, Patients Receiving Self-Esteem Training Had Extended Antidepressant Benefits, Study Finds

Folic Acid Supplements Were Associated With Lower Suicidality in Large Database Study

READ

Posted: Thursday, October 13, 2022

Folic Acid Supplements Were Associated With Lower Suicidality in Large Database Study

Two Forms of Non-Invasive Brain Stimulation Helped Older Adults with Treatment-Resistant Depression

READ

Posted: Thursday, October 6, 2022

Two Forms of Non-Invasive Brain Stimulation Helped Older Adults with Treatment-Resistant Depression

Long-Term Regular Cannabis Users Showed Cognitive Deficits at Midlife in 45-Year Study

READ

Posted: Thursday, September 29, 2022

Long-Term Regular Cannabis Users Showed Cognitive Deficits at Midlife in 45-Year Study

Exposures to Poverty and Crime in Pregnancy Found to Perturb Prenatal Brain Development

READ

Posted: Thursday, September 22, 2022

Exposures to Poverty and Crime in Pregnancy Found to Perturb Prenatal Brain Development

FDA Clears SAINT Rapid-Acting Brain Stimulation Approach for Those Suffering From Resistant Major Depression

READ

Posted: Thursday, September 15, 2022

FDA Clears SAINT Rapid-Acting Brain Stimulation Approach for Those Suffering From Resistant Major Depression

How an ‘Active Coping Style’ Helps New Mothers Deal With Stresses of Parenthood

READ

Posted: Thursday, September 8, 2022

How an ‘Active Coping Style’ Helps New Mothers Deal With Stresses of Parenthood

In Large Study, Those Diagnosed with a Psychiatric Disorder Were More Likely to Develop Dementia

READ

Posted: Thursday, September 1, 2022

In Large Study, Those Diagnosed with a Psychiatric Disorder Were More Likely to Develop Dementia

The last decade has seen a vast increase in the use of brain stimulation technologies to reduce symptoms of psychiatric illness. By far the most influential has been TMS, a non-invasive method employing magnets that generate electric fields which are thought to therapeutically alter the activity of neurons and brain circuits involved in depression and other disorders. TMS was pioneered by BBRF Scientific Council member Mark S. George, M.D., who used two early-career BBRF grants to develop the protocol ul

READ

Posted: Thursday, August 25, 2022

Team Assesses Safety of t-PBM, Non-Invasive Brain Stimulation Technology That Uses Light to Treat Depression and Anxiety

The Neurobiology Behind Young People’s Shift in Interest From Mother’s Voice to Those of Non-Family Members

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Posted: Thursday, August 18, 2022

The Neurobiology Behind Young People’s Shift in Interest From Mother’s Voice to Those of Non-Family Members

Risk of Anxiety Disorder Is Greater in Children Whose Same-Sex Parent Has an Anxiety Disorder, Study Finds

READ

Posted: Thursday, August 11, 2022

Risk of Anxiety Disorder Is Greater in Children Whose Same-Sex Parent Has an Anxiety Disorder, Study Finds

Researchers Identify Molecule That Orchestrates Association of Events With Positive and Negative Memories

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Posted: Thursday, August 4, 2022

Researchers Identify Molecule That Orchestrates Association of Events With Positive and Negative Memories

Researchers Identify a Neural Signature Centrally Important in Restructuring Negative Self-Beliefs

READ

Posted: Thursday, July 28, 2022

Researchers Identify a Neural Signature Centrally Important in Restructuring Negative Self-Beliefs

Comprehensive Analysis Suggests Metacognitive Training Can Be Effective in Schizophrenia and Psychotic Disorders

READ

Posted: Wednesday, July 20, 2022

Comprehensive Analysis Suggests Metacognitive Training Can Be Effective in Schizophrenia and Psychotic Disorders

1-Day Online CBT-Based Workshop Helped New Moms With Postpartum Depression

READ

Posted: Tuesday, July 12, 2022

1-Day Online CBT-Based Workshop Helped New Moms With Postpartum Depression

Some OCD Patients Who Attain “Wellness” After Exposure Therapy May Safely Taper Off Their SRI Medicines, Study Suggests

READ

Posted: Thursday, July 7, 2022

Some OCD Patients Who Attain “Wellness” After Exposure Therapy May Safely Taper Off Their SRI Medicines, Study Suggests

A Circuit Causally Linked With Spontaneous Nicotine Addiction Remissions May Be a Powerful Addiction Treatment Target

READ

Posted: Thursday, June 30, 2022

A Circuit Causally Linked With Spontaneous Nicotine Addiction Remissions May Be a Powerful Addiction Treatment Target

Children of Mothers Infected by COVID in Pregnancy Had Increased Risk of a Developmental Disorder Diagnosis at 1 Year

READ

Posted: Thursday, June 23, 2022

Children of Mothers Infected by COVID in Pregnancy Had Increased Risk of a Developmental Disorder Diagnosis at 1 Year

Researchers Discover Potentially Targetable Brain Circuit Controlling Cocaine Withdrawal Anxiety and Relapse

READ

Posted: Thursday, June 16, 2022

Researchers Discover Potentially Targetable Brain Circuit Controlling Cocaine Withdrawal Anxiety and Relapse

Combining Antidepressants Can Improve Outcomes in Patients with Severe Depression, Study Finds

READ

Posted: Thursday, June 9, 2022

Combining Antidepressants Can Improve Outcomes in Patients with Severe Depression, Study Finds

Maternal Sleep Apnea in Pregnancy Is Linked in Animal Model With Autism-like Behavioral Impacts in Offspring

READ

Posted: Thursday, June 2, 2022

Maternal Sleep Apnea in Pregnancy Is Linked in Animal Model With Autism-like Behavioral Impacts in Offspring

A Molecule Tested in Higher Primates Reduced Alcohol Consumption By Half

READ

Posted: Thursday, May 26, 2022

A Molecule Tested in Higher Primates Reduced Alcohol Consumption By Half

Difficulty Updating Prior Knowledge With New Perceptions Is Linked by Researchers With Psychosis Symptoms

READ

Posted: Thursday, May 19, 2022

Difficulty Updating Prior Knowledge With New Perceptions Is Linked by Researchers With Psychosis Symptoms

Precise Imaging Reveals How a Key Receptor's Signaling Is Modulated—A Spur to Improving Psychiatric and Other Drugs

READ

Posted: Thursday, May 12, 2022

Precise Imaging Reveals How a Key Receptor's Signaling Is Modulated—A Spur to Improving Psychiatric and Other Drugs

Stem Cell Technology Helps Identify a Potential Causal Mechanism in Schizophrenia That Could Be Targeted

READ

Posted: Thursday, May 5, 2022

Stem Cell Technology Helps Identify a Potential Causal Mechanism in Schizophrenia That Could Be Targeted

A 'Common Causal Circuit' in Depression with Possible Therapeutic Implications

READ

Posted: Wednesday, May 4, 2022

A 'Common Causal Circuit' in Depression with Possible Therapeutic Implications

New Insights About Epilepsy Mechanism Suggest a Potential Treatment Target

READ

Posted: Thursday, April 28, 2022

New Insights About Epilepsy Mechanism Suggest a Potential Treatment Target

News and Events

READ

Webinar

Thursday, December 1, 2022, 7:00 pm EST

Warning Signs & What to Look for: Anxiety and Depression in Childhood

READ

BLOG

Wednesday, December 29, 2021

2021 Leading Research Achievements

READ

Foundation Event

Friday, October 28, 2022

International Mental Health Research Symposium

READ

Webinar

Tuesday, January 11, 2022, 2:00 pm EST

Prenatal Exposures and Experiences: Impact on Children’s Early Brain Development and Risk for Disease

READ

Webinar

Tuesday, December 14, 2021, 2:00 pm EST

OCD: Using Genome Data to Predict Risk, Symptoms and Treatment Response

READ

Webinar

Tuesday, November 9, 2021, 2:00 pm EST

Developing New Treatments for Mania Using Brain-Based Risk Markers

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100% of every dollar donated for research is invested in our research grants. Our operating expenses are covered by separate foundation grants.

The Brain & Behavior Research Foundation is a 501(c)(3) nonprofit organization, our Tax ID # is 31-1020010.

Research

Research

1 in 5 of Us Lives With a Mental Illness

Addiction

Attention-Deficit Hyperactivity Disorder (ADHD)

Anxiety

Autism

Bipolar Disorder

Borderline Personality Disorder

Depression

Eating Disorders

Obsessive-Compulsive Disorder (OCD)

Post-Traumatic Stress Disorder (PTSD)

Schizophrenia

Mental Illness (General)

Research Categories

Basic Research

New Technologies

Diagnostic Tools / Early Intervention

Next-Generation Therapies

Research Articles

Important New Research on Schizophrenia Genetics Provides Strongest Evidence to Date of Problems at the Brain’s Synapses

Video Game-Based Intervention Helped Reduce Cognitive Deficits in Depressed Patients

Clinical Trial Compared Different Forms of Exposure and Drug Therapy in Combat Veterans with PTSD

Adding an Antibiotic Improved Brain Stimulation Results in Depression

Lab-Grown Human Neurons Transplanted into the Rat Brain Grew, Connected, and Promise to Shed Light on Psychiatric Illness

After ‘Priming’ with Ketamine, Patients Receiving Self-Esteem Training Had Extended Antidepressant Benefits, Study Finds

Folic Acid Supplements Were Associated With Lower Suicidality in Large Database Study

Two Forms of Non-Invasive Brain Stimulation Helped Older Adults with Treatment-Resistant Depression

Long-Term Regular Cannabis Users Showed Cognitive Deficits at Midlife in 45-Year Study

Exposures to Poverty and Crime in Pregnancy Found to Perturb Prenatal Brain Development

FDA Clears SAINT Rapid-Acting Brain Stimulation Approach for Those Suffering From Resistant Major Depression

How an ‘Active Coping Style’ Helps New Mothers Deal With Stresses of Parenthood

In Large Study, Those Diagnosed with a Psychiatric Disorder Were More Likely to Develop Dementia

Team Assesses Safety of t-PBM, Non-Invasive Brain Stimulation Technology That Uses Light to Treat Depression and Anxiety

The Neurobiology Behind Young People’s Shift in Interest From Mother’s Voice to Those of Non-Family Members

Risk of Anxiety Disorder Is Greater in Children Whose Same-Sex Parent Has an Anxiety Disorder, Study Finds

Researchers Identify Molecule That Orchestrates Association of Events With Positive and Negative Memories

Researchers Identify a Neural Signature Centrally Important in Restructuring Negative Self-Beliefs

Comprehensive Analysis Suggests Metacognitive Training Can Be Effective in Schizophrenia and Psychotic Disorders

1-Day Online CBT-Based Workshop Helped New Moms With Postpartum Depression

Some OCD Patients Who Attain “Wellness” After Exposure Therapy May Safely Taper Off Their SRI Medicines, Study Suggests

A Circuit Causally Linked With Spontaneous Nicotine Addiction Remissions May Be a Powerful Addiction Treatment Target

Children of Mothers Infected by COVID in Pregnancy Had Increased Risk of a Developmental Disorder Diagnosis at 1 Year

Researchers Discover Potentially Targetable Brain Circuit Controlling Cocaine Withdrawal Anxiety and Relapse

Combining Antidepressants Can Improve Outcomes in Patients with Severe Depression, Study Finds

Maternal Sleep Apnea in Pregnancy Is Linked in Animal Model With Autism-like Behavioral Impacts in Offspring

A Molecule Tested in Higher Primates Reduced Alcohol Consumption By Half

Difficulty Updating Prior Knowledge With New Perceptions Is Linked by Researchers With Psychosis Symptoms

Precise Imaging Reveals How a Key Receptor's Signaling Is Modulated—A Spur to Improving Psychiatric and Other Drugs

Stem Cell Technology Helps Identify a Potential Causal Mechanism in Schizophrenia That Could Be Targeted

A 'Common Causal Circuit' in Depression with Possible Therapeutic Implications

New Insights About Epilepsy Mechanism Suggest a Potential Treatment Target

News and Events

Warning Signs & What to Look for: Anxiety and Depression in Childhood

2021 Leading Research Achievements

International Mental Health Research Symposium

Prenatal Exposures and Experiences: Impact on Children’s Early Brain Development and Risk for Disease

OCD: Using Genome Data to Predict Risk, Symptoms and Treatment Response

Developing New Treatments for Mania Using Brain-Based Risk Markers

Donate Now

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