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Schizophrenia

Schizophrenia

$150M Awarded to Schizophrenia Research since 1987

Learn about Schizophrenia

The Latest Research Discoveries

In Schizophrenia, Differences in the Brain’s Energy Pathways Suggest Possible New Treatment Target

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Posted: Thursday, February 18, 2021

In Schizophrenia, Differences in the Brain’s Energy Pathways Suggest Possible New Treatment Target

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People With Schizophrenia Have Increased Risk of Dying From COVID-19, Research Reveals

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Posted: Thursday, February 4, 2021

People With Schizophrenia Have Increased Risk of Dying From COVID-19, Research Reveals

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Combining the Antipsychotic Olanzapine with an Opioid-Receptor Blocker Significantly Limited Weight-Gain Risk in Schizophrenia Patients

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Posted: Thursday, January 28, 2021

Combining the Antipsychotic Olanzapine with an Opioid-Receptor Blocker Significantly Limited Weight-Gain Risk in Schizophrenia Patients

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Study Reveals Adults With Mental Disorders Are At Significantly Higher Risk of COVID-19 and Have Poorer Outcomes

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Posted: Thursday, November 12, 2020

Study Reveals Adults With Mental Disorders Are At Significantly Higher Risk of COVID-19 and Have Poorer Outcomes

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Researchers Discover a Role for Immune Cells Called Microglia in Inhibiting Brain Activity and Regulating Behavior

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Posted: Thursday, October 29, 2020

Researchers Discover a Role for Immune Cells Called Microglia in Inhibiting Brain Activity and Regulating Behavior

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Drugs Targeting the Glutamate System Warrant Continued Development for Schizophrenia, Study Finds

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Posted: Thursday, October 22, 2020

Drugs Targeting the Glutamate System Warrant Continued Development for Schizophrenia, Study Finds

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New Study Demonstrates Non-Invasive tDCS Brain Stimulation Can Enhance Cognitive Control in Schizophrenia Patients

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Posted: Thursday, October 8, 2020

New Study Demonstrates Non-Invasive tDCS Brain Stimulation Can Enhance Cognitive Control in Schizophrenia Patients

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Study Makes Case for Rigorous Re-Testing of Opioid Antagonists to Treat Schizophrenia

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Posted: Thursday, October 1, 2020

Study Makes Case for Rigorous Re-Testing of Opioid Antagonists to Treat Schizophrenia

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Large Genetic Study Expands Links Between DNA Variations and Problematic Drinking

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Posted: Thursday, September 17, 2020

Large Genetic Study Expands Links Between DNA Variations and Problematic Drinking

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Researchers Discover Proteins in the Brain That Protect Synapses From Being Eliminated

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Posted: Thursday, September 3, 2020

Researchers Discover Proteins in the Brain That Protect Synapses From Being Eliminated

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Brainwave Study Reveals Oscillation Patterns That May Predict Transition to Psychosis

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Posted: Thursday, August 20, 2020

Brainwave Study Reveals Oscillation Patterns That May Predict Transition to Psychosis

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Genome Engineering Combined with Stem Cell Technology Provide Insights on Disruptions in Brain Development

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Posted: Thursday, April 23, 2020

Genome Engineering Combined with Stem Cell Technology Provide Insights on Disruptions in Brain Development

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Taking the Next Step in Understanding the Genetic Roots of Mental Illness

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Posted: Tuesday, March 31, 2020

Taking the Next Step in Understanding the Genetic Roots of Mental Illness

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Connecting the Dots, From Genes to Brain Biology to Disorders

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Posted: Tuesday, March 31, 2020

Connecting the Dots, From Genes to Brain Biology to Disorders

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Progress is Reported on Research Exploring Use of Deep-Brain Stimulation for Psychosis, Schizophrenia

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Posted: Thursday, March 26, 2020

Progress is Reported on Research Exploring Use of Deep-Brain Stimulation for Psychosis, Schizophrenia

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Maternal Inflammation Early in Pregnancy May Raise Offspring’s Psychosis Risk

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Posted: Thursday, February 20, 2020

Maternal Inflammation Early in Pregnancy May Raise Offspring’s Psychosis Risk

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New Approach to Lessen Negative Symptoms in Schizophrenia is Based on Brain Circuit Discovery

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Posted: Thursday, January 16, 2020

New Approach to Lessen Negative Symptoms in Schizophrenia is Based on Brain Circuit Discovery

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Higher Maternal Choline Levels in Pregnancy Had Protective Role in Infant Brain Development

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Posted: Thursday, January 9, 2020

Higher Maternal Choline Levels in Pregnancy Had Protective Role in Infant Brain Development

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Imaging Study Links Changes in Function and Structure of the Hippocampus in Early Psychosis

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Posted: Thursday, November 21, 2019

Imaging Study Links Changes in Function and Structure of the Hippocampus in Early Psychosis

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60 year study finds children of mothers who contracted bacterial infection during pregnancy have higher risk of psychosis

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Posted: Thursday, November 14, 2019

After 60 Years, Study Finds Children of Mothers with Bacterial Infections During Pregnancy Have Elevated Psychosis Risk

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Study Links an Early-Life Abnormality in the Auditory Cortex with Vulnerability to Hallucinations in Schizophrenia

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Posted: Thursday, October 24, 2019

Study Links an Early-Life Abnormality in the Auditory Cortex with Vulnerability to Hallucinations in Schizophrenia

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Low Levels of Cannabinoid Receptor in New Psychosis Patients Suggest a Possible Drug Target

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Posted: Thursday, September 19, 2019

Low Levels of Cannabinoid Receptor in New Psychosis Patients Suggest a Possible Drug Target

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A Way of Predicting if New Psychosis Patients Will or Won’t Respond to Standard Treatment

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Posted: Thursday, August 1, 2019

A Way of Predicting if New Psychosis Patients Will or Won’t Respond to Standard Treatment

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RESEARCH FOR RECOVERY: Advances in Cognitive Remediation: ‘Helping Schizophrenia Patients Who Need It Most’

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Posted: Sunday, June 30, 2019

RESEARCH FOR RECOVERY: Advances in Cognitive Remediation: ‘Helping Schizophrenia Patients Who Need It Most’

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A Rarely Studied Brain Structure Provides New Clues About Psychosis

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Posted: Thursday, June 27, 2019

A Rarely Studied Brain Structure Provides New Clues About Psychosis

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Evidence Links Abnormally Formed Proteins With Schizophrenia Pathology in Some Patients

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Posted: Thursday, June 13, 2019

Evidence Links Abnormally Formed Proteins With Schizophrenia Pathology in Some Patients

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Research on Antioxidant Role in Schizophrenia and Psychosis Points to Possible Therapeutic Value of Compound Found in Broccoli

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Posted: Thursday, May 30, 2019

Research on Antioxidant Role in Schizophrenia and Psychosis Points to Possible Therapeutic Value of Compound Found in Broccoli

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In a Comparison of Two Kinds of Cognitive Training, One Appeared to Help Schizophrenia Patients More

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Posted: Tuesday, April 9, 2019

In a Comparison of Two Kinds of Cognitive Training, One Appeared to Help Schizophrenia Patients More

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Adding Guanfacine Boosted Benefits of Cognitive Remediation Therapy in Schizophrenia Spectrum Disorder

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Posted: Wednesday, January 30, 2019

Adding Guanfacine Boosted Benefits of Cognitive Remediation Therapy in Schizophrenia Spectrum Disorder

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Researchers Study ‘Background’ Mutations That Can Impact Schizophrenia and Autism

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Posted: Monday, January 14, 2019

Researchers Study ‘Background’ Mutations That Can Impact Schizophrenia and Autism

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The Brain Continues to Develop in Young People With Schizophrenia

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Posted: Monday, November 5, 2018

The Brain Continues to Develop in Young People With Schizophrenia

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Computer-Delivered Cognitive Training Significantly Helped Schizophrenia Patients in Rehab Setting

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Posted: Monday, October 22, 2018

Computer-Delivered Cognitive Training Significantly Helped Schizophrenia Patients in Rehab Setting

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Key Figures

3.5 million adults

3.5 million adults (1.1%) of the US Adult population live with schizophrenia*

* Source: National Institute of Mental Health

21 million

More than 21 million people worldwide are affected by schizophrenia*

* Source: World Health Organization (WHO)

Featured Tweet

New risk genes for #schizophrenia have been discovered by studying DNA in highly compressed bundles. TWEET

Meet a Researcher

Robert R. Freedman, M.D.
Read Full Bio
Robert R. Freedman, M.D.

Professor and Chairman

2006, 1999 Distinguished Investigator Grant

Ask an Expert

Huda Akil, Ph.D. - Brain & behavior research expert on depression
Read the answer
Huda Akil, Ph.D.

Gardner Quarton Distinguished University Professor of Neuroscience and Psychiatry

Co-Director, Molecular and Behavioral Neuroscience Institute

University of Michigan

2007 Goldman-Rakic Prize for Outstanding Achievement in Cognitive Neuroscience

Question:

In your work with the Pritzker Neuropsychiatric Research Consortium, have you uncovered any new genes that you think might be related to mental illnesses besides major depression?

Donor Stories

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Focus on Family Support


Ann Laitman’s son, Daniel, was diagnosed with schizophrenia when he was 15. Daniel is now 19, and with treatment and family support, he is making...

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Follow-Up: 'Team Daniel' Runs for NARSAD


We met Daniel Laitman and his parents Ann and Rob in the September 2010 issue of eNews from NARSAD. Daniel is 19 and lives with schizophrenia. [...

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One Young Man’s Rocky Road to Recovery


Overcoming the challenge of living with symptoms of schizophrenia and bipolar disorder – a mix seen more often in men From The Quarterly, Fall 2011...

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Late-Onset Mental Illness Unravels a Family's Life


Among Janet Larsen’s family mementos, carefully preserved and passed down by her mother, is a letter addressed to Janet’s father, Victor Lottmann, on...

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Social Media Helps One Man Institutionalized for Schizophrenia Reconnect with Old Friends


The summer before Neil Barber’s junior year in high school, he and three of his buddies decided to experiment with marijuana. Neil’s dad, Greg,...

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The Crucial Need for Brain Research: A Leader at NAMI Discusses Her Unwavering 25-Year Support of the Brain & Behavior Research Foundation


From The Quarterly, Spring 2012 Like many donors to the Brain & Behavior Research Foundation, Janet and Myron Susin of Long Island, New York,...

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Well Into Recovery


From The Quarterly, Spring 2013 Recalling her son’s last year in high school, Stamatia Pappas can still, ten years later, feel her eyes fill with...

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Heartache And Hard-Won Progress


Love, support and good education: not enough to preclude mental illness in this family, but enough to help them cultivate recovery From The Quarterly...

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In Schizophrenia’s Wake, a Son Laments the Father Who Might Have Been


Emerson Hart is a singer-songwriter. In the 1990s, he co-founded the Grammy-nominated rock band Tonic and, as the lead singer, has written hit...

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From Chaos to Hope: A Family’s Odyssey with Schizophrenia


Seared into Randye Kaye’s memory is a terrifying day in 2003 when she rushed 21-year-old Ben to the emergency room of the local hospital near her...

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An Agonizing Journey and a “Blessing”


Janet and Donald Boardman, Sr., remember with chilling clarity the last time their son Donald, Jr., had to be hospitalized against his will. “When...

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