Schizophrenia

The Latest Research Discoveries

Difficulty Updating Prior Knowledge With New Perceptions Is Linked by Researchers With Psychosis Symptoms

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Posted: Thursday, May 19, 2022

Difficulty Updating Prior Knowledge With New Perceptions Is Linked by Researchers With Psychosis Symptoms

Precise Imaging Reveals How a Key Receptor's Signaling Is Modulated—A Spur to Improving Psychiatric and Other Drugs

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Posted: Thursday, May 12, 2022

Precise Imaging Reveals How a Key Receptor's Signaling Is Modulated—A Spur to Improving Psychiatric and Other Drugs

Stem Cell Technology Helps Identify a Potential Casual Mechanism in Schizophrenia That Could Be Targeted

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Posted: Thursday, May 5, 2022

Stem Cell Technology Helps Identify a Potential Casual Mechanism in Schizophrenia That Could Be Targeted

In Hippocampus, Protein's Malfunction Is Potential Link to Memory and Other Impairments Seen in Schizophrenia

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Posted: Thursday, March 17, 2022

In Hippocampus, Protein's Malfunction Is Potential Link to Memory and Other Impairments Seen in Schizophrenia

Sensory and Motor-System Abnormalities May Help Identify High-Risk Individuals Who Will Develop Psychosis

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Posted: Thursday, January 27, 2022

Sensory and Motor-System Abnormalities May Help Identify High-Risk Individuals Who Will Develop Psychosis

Study Reveals How Gene Regulation Helps Determine Brain Development, Shedding Light on Neurodevelopmental Disorders

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Posted: Thursday, December 9, 2021

Study Reveals How Gene Regulation Helps Determine Brain Development, Shedding Light on Neurodevelopmental Disorders

Researchers Propose a New Understanding of Dopamine's Role in Learning and Memory

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Posted: Thursday, September 30, 2021

Researchers Propose a New Understanding of Dopamine's Role in Learning and Memory

Obesity Is a Risk Factor for Brain-Structure Changes in Schizophrenia and Bipolar Disorder, 2 Studies Show

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Posted: Thursday, August 12, 2021

Obesity Is a Risk Factor for Brain-Structure Changes in Schizophrenia and Bipolar Disorder, 2 Studies Show

Negative Symptoms in Schizophrenia Worsened Under Pandemic Conditions, Study Finds

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Posted: Thursday, July 8, 2021

Negative Symptoms in Schizophrenia Worsened Under Pandemic Conditions, Study Finds

Study Links Schizophrenia Medicines’ Anticholinergic Impact to Risk of Cognitive Impairment

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Posted: Thursday, July 1, 2021

Study Links Schizophrenia Medicines’ Anticholinergic Impact to Risk of Cognitive Impairment

Experiments Reveal How a Circuit 'Resets' When the Brain Learns to Respond to New Conditions

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Posted: Monday, June 21, 2021

Experiments Reveal How a Circuit 'Resets' When the Brain Learns to Respond to New Conditions

Testing a Computer-Generated Model to Predict High-Risk Youths' Transition to Psychosis

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Posted: Thursday, May 27, 2021

Testing a Computer-Generated Model to Predict High-Risk Youths' Transition to Psychosis

Using Brainwave Patterns to Predict and Understand Psychiatric Disorders

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Posted: Wednesday, May 5, 2021

Using Brainwave Patterns to Predict and Understand Psychiatric Disorders

In Early Schizophrenia, Long-Acting Injectable Antipsychotic Treatment Lengthened Time to First Hospitalization

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Posted: Thursday, March 25, 2021

In Early Schizophrenia, Long-Acting Injectable Antipsychotic Treatment Lengthened Time to First Hospitalization

Hyperactivity in Two Wide-Ranging Neural Networks is Discovered in Schizophrenia Patients

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Posted: Thursday, March 18, 2021

Hyperactivity in Two Wide-Ranging Neural Networks is Discovered in Schizophrenia Patients

In Schizophrenia, Differences in the Brain’s Energy Pathways Suggest Possible New Treatment Target

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Posted: Thursday, February 18, 2021

In Schizophrenia, Differences in the Brain’s Energy Pathways Suggest Possible New Treatment Target

People With Schizophrenia Have Increased Risk of Dying From COVID-19, Research Reveals

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Posted: Thursday, February 4, 2021

People With Schizophrenia Have Increased Risk of Dying From COVID-19, Research Reveals

Combining the Antipsychotic Olanzapine with an Opioid-Receptor Blocker Significantly Limited Weight-Gain Risk in Schizophrenia Patients

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Posted: Thursday, January 28, 2021

Combining the Antipsychotic Olanzapine with an Opioid-Receptor Blocker Significantly Limited Weight-Gain Risk in Schizophrenia Patients

Study Reveals Adults With Mental Disorders Are At Significantly Higher Risk of COVID-19 and Have Poorer Outcomes

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Posted: Thursday, November 12, 2020

Study Reveals Adults With Mental Disorders Are At Significantly Higher Risk of COVID-19 and Have Poorer Outcomes

Researchers Discover a Role for Immune Cells Called Microglia in Inhibiting Brain Activity and Regulating Behavior

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Posted: Thursday, October 29, 2020

Researchers Discover a Role for Immune Cells Called Microglia in Inhibiting Brain Activity and Regulating Behavior

Drugs Targeting the Glutamate System Warrant Continued Development for Schizophrenia, Study Finds

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Posted: Thursday, October 22, 2020

Drugs Targeting the Glutamate System Warrant Continued Development for Schizophrenia, Study Finds

New Study Demonstrates Non-Invasive tDCS Brain Stimulation Can Enhance Cognitive Control in Schizophrenia Patients

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Posted: Thursday, October 8, 2020

New Study Demonstrates Non-Invasive tDCS Brain Stimulation Can Enhance Cognitive Control in Schizophrenia Patients

Study Makes Case for Rigorous Re-Testing of Opioid Antagonists to Treat Schizophrenia

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Posted: Thursday, October 1, 2020

Study Makes Case for Rigorous Re-Testing of Opioid Antagonists to Treat Schizophrenia

Large Genetic Study Expands Links Between DNA Variations and Problematic Drinking

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Posted: Thursday, September 17, 2020

Large Genetic Study Expands Links Between DNA Variations and Problematic Drinking

Researchers Discover Proteins in the Brain That Protect Synapses From Being Eliminated

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Posted: Thursday, September 3, 2020

Researchers Discover Proteins in the Brain That Protect Synapses From Being Eliminated

Brainwave Study Reveals Oscillation Patterns That May Predict Transition to Psychosis

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Posted: Thursday, August 20, 2020

Brainwave Study Reveals Oscillation Patterns That May Predict Transition to Psychosis

Genome Engineering Combined with Stem Cell Technology Provide Insights on Disruptions in Brain Development

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Posted: Thursday, April 23, 2020

Genome Engineering Combined with Stem Cell Technology Provide Insights on Disruptions in Brain Development

Taking the Next Step in Understanding the Genetic Roots of Mental Illness

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Posted: Tuesday, March 31, 2020

Taking the Next Step in Understanding the Genetic Roots of Mental Illness

Connecting the Dots, From Genes to Brain Biology to Disorders

READ

Posted: Tuesday, March 31, 2020

Connecting the Dots, From Genes to Brain Biology to Disorders

Progress is Reported on Research Exploring Use of Deep-Brain Stimulation for Psychosis, Schizophrenia

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Posted: Thursday, March 26, 2020

Progress is Reported on Research Exploring Use of Deep-Brain Stimulation for Psychosis, Schizophrenia

Maternal Inflammation Early in Pregnancy May Raise Offspring’s Psychosis Risk

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Posted: Thursday, February 20, 2020

Maternal Inflammation Early in Pregnancy May Raise Offspring’s Psychosis Risk

New Approach to Lessen Negative Symptoms in Schizophrenia is Based on Brain Circuit Discovery

READ

Posted: Thursday, January 16, 2020

New Approach to Lessen Negative Symptoms in Schizophrenia is Based on Brain Circuit Discovery

Key Figures

3.5 million adults

3.5 million adults (1.1%) of the US Adult population live with schizophrenia*

* Source: National Institute of Mental Health

21 million

More than 21 million people worldwide are affected by schizophrenia*

* Source: World Health Organization (WHO)

Featured Tweet

New risk genes for #schizophrenia have been discovered by studying DNA in highly compressed bundles. TWEET

Meet a Researcher

Read Full Bio

Amy F.T. Arnsten, Ph.D.

Albert E. Kent Professor of Neuroscience and of Psychology

Yale School of Medicine

1998 Independent Investigator Grant

Ask an Expert

Read the answer

Huda Akil, Ph.D.

Gardner Quarton Distinguished University Professor of Neuroscience and Psychiatry

Co-Director, Molecular and Behavioral Neuroscience Institute

University of Michigan

2007 Goldman-Rakic Prize for Outstanding Achievement in Cognitive Neuroscience

Question:

In your work with the Pritzker Neuropsychiatric Research Consortium, have you uncovered any new genes that you think might be related to mental illnesses besides major depression?

Donor Stories

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An Agonizing Journey and a “Blessing”

Janet and Donald Boardman, Sr., remember with chilling clarity the last time their son Donald, Jr., had to be hospitalized against his will. “When...

READ

In Schizophrenia’s Wake, a Son Laments the Father Who Might Have Been

Emerson Hart is a singer-songwriter. In the 1990s, he co-founded the Grammy-nominated rock band Tonic and, as the lead singer, has written hit...

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Focus on Family Support

Ann Laitman’s son, Daniel, was diagnosed with schizophrenia when he was 15. Daniel is now 19, and with treatment and family support, he is making...

READ

Heartache And Hard-Won Progress

Love, support and good education: not enough to preclude mental illness in this family, but enough to help them cultivate recovery From The Quarterly...

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Social Media Helps One Man Institutionalized for Schizophrenia Reconnect with Old Friends

The summer before Neil Barber’s junior year in high school, he and three of his buddies decided to experiment with marijuana. Neil’s dad, Greg,...

READ

From Chaos to Hope: A Family’s Odyssey with Schizophrenia

Seared into Randye Kaye’s memory is a terrifying day in 2003 when she rushed 21-year-old Ben to the emergency room of the local hospital near her...

READ

One Young Man’s Rocky Road to Recovery

Overcoming the challenge of living with symptoms of schizophrenia and bipolar disorder – a mix seen more often in men From The Quarterly, Fall 2011...

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Late-Onset Mental Illness Unravels a Family's Life

Among Janet Larsen’s family mementos, carefully preserved and passed down by her mother, is a letter addressed to Janet’s father, Victor Lottmann, on...

READ

The Crucial Need for Brain Research: A Leader at NAMI Discusses Her Unwavering 25-Year Support of the Brain & Behavior Research Foundation

From The Quarterly, Spring 2012 Like many donors to the Brain & Behavior Research Foundation, Janet and Myron Susin of Long Island, New York,...

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Well Into Recovery

From The Quarterly, Spring 2013 Recalling her son’s last year in high school, Stamatia Pappas can still, ten years later, feel her eyes fill with...

READ

Follow-Up: 'Team Daniel' Runs for NARSAD

We met Daniel Laitman and his parents Ann and Rob in the September 2010 issue of eNews from NARSAD. Daniel is 19 and lives with schizophrenia. [...

News and Events

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BLOG

Wednesday, December 29, 2021

2021 Leading Research Achievements

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Foundation Event

Friday, October 29, 2021

International Mental Health Research Symposium

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Webinar

Tuesday, January 11, 2022, 2:00 pm EST

Prenatal Exposures and Experiences: Impact on Children’s Early Brain Development and Risk for Disease

READ

Webinar

Tuesday, December 14, 2021, 2:00 pm EST

OCD: Using Genome Data to Predict Risk, Symptoms and Treatment Response

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Webinar

Tuesday, November 9, 2021, 2:00 pm EST

Developing New Treatments for Mania Using Brain-Based Risk Markers

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BLOG

Friday, April 16, 2021

2020 International Mental Health Research Symposium Presentations

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Schizophrenia

Schizophrenia

The Latest Research Discoveries

Difficulty Updating Prior Knowledge With New Perceptions Is Linked by Researchers With Psychosis Symptoms

Precise Imaging Reveals How a Key Receptor's Signaling Is Modulated—A Spur to Improving Psychiatric and Other Drugs

Stem Cell Technology Helps Identify a Potential Casual Mechanism in Schizophrenia That Could Be Targeted

In Hippocampus, Protein's Malfunction Is Potential Link to Memory and Other Impairments Seen in Schizophrenia

Sensory and Motor-System Abnormalities May Help Identify High-Risk Individuals Who Will Develop Psychosis

Study Reveals How Gene Regulation Helps Determine Brain Development, Shedding Light on Neurodevelopmental Disorders

Researchers Propose a New Understanding of Dopamine's Role in Learning and Memory

Obesity Is a Risk Factor for Brain-Structure Changes in Schizophrenia and Bipolar Disorder, 2 Studies Show

Negative Symptoms in Schizophrenia Worsened Under Pandemic Conditions, Study Finds

Study Links Schizophrenia Medicines’ Anticholinergic Impact to Risk of Cognitive Impairment

Experiments Reveal How a Circuit 'Resets' When the Brain Learns to Respond to New Conditions

Testing a Computer-Generated Model to Predict High-Risk Youths' Transition to Psychosis

Using Brainwave Patterns to Predict and Understand Psychiatric Disorders

In Early Schizophrenia, Long-Acting Injectable Antipsychotic Treatment Lengthened Time to First Hospitalization

Hyperactivity in Two Wide-Ranging Neural Networks is Discovered in Schizophrenia Patients

In Schizophrenia, Differences in the Brain’s Energy Pathways Suggest Possible New Treatment Target

People With Schizophrenia Have Increased Risk of Dying From COVID-19, Research Reveals

Combining the Antipsychotic Olanzapine with an Opioid-Receptor Blocker Significantly Limited Weight-Gain Risk in Schizophrenia Patients

Study Reveals Adults With Mental Disorders Are At Significantly Higher Risk of COVID-19 and Have Poorer Outcomes

Researchers Discover a Role for Immune Cells Called Microglia in Inhibiting Brain Activity and Regulating Behavior

Drugs Targeting the Glutamate System Warrant Continued Development for Schizophrenia, Study Finds

New Study Demonstrates Non-Invasive tDCS Brain Stimulation Can Enhance Cognitive Control in Schizophrenia Patients

Study Makes Case for Rigorous Re-Testing of Opioid Antagonists to Treat Schizophrenia

Large Genetic Study Expands Links Between DNA Variations and Problematic Drinking

Researchers Discover Proteins in the Brain That Protect Synapses From Being Eliminated

Brainwave Study Reveals Oscillation Patterns That May Predict Transition to Psychosis

Genome Engineering Combined with Stem Cell Technology Provide Insights on Disruptions in Brain Development

Taking the Next Step in Understanding the Genetic Roots of Mental Illness

Connecting the Dots, From Genes to Brain Biology to Disorders

Progress is Reported on Research Exploring Use of Deep-Brain Stimulation for Psychosis, Schizophrenia

Maternal Inflammation Early in Pregnancy May Raise Offspring’s Psychosis Risk

New Approach to Lessen Negative Symptoms in Schizophrenia is Based on Brain Circuit Discovery

Key Figures

Featured Tweet

Meet a Researcher

Amy F.T. Arnsten, Ph.D.

Ask an Expert

Huda Akil, Ph.D.

In your work with the Pritzker Neuropsychiatric Research Consortium, have you uncovered any new genes that you think might be related to mental illnesses besides major depression?

Donor Stories

An Agonizing Journey and a “Blessing”

In Schizophrenia’s Wake, a Son Laments the Father Who Might Have Been

Focus on Family Support

Heartache And Hard-Won Progress

Social Media Helps One Man Institutionalized for Schizophrenia Reconnect with Old Friends

From Chaos to Hope: A Family’s Odyssey with Schizophrenia

One Young Man’s Rocky Road to Recovery

Late-Onset Mental Illness Unravels a Family's Life

The Crucial Need for Brain Research: A Leader at NAMI Discusses Her Unwavering 25-Year Support of the Brain & Behavior Research Foundation

Well Into Recovery

Follow-Up: 'Team Daniel' Runs for NARSAD

News and Events

2021 Leading Research Achievements

International Mental Health Research Symposium

Prenatal Exposures and Experiences: Impact on Children’s Early Brain Development and Risk for Disease

OCD: Using Genome Data to Predict Risk, Symptoms and Treatment Response

Developing New Treatments for Mania Using Brain-Based Risk Markers

2020 International Mental Health Research Symposium Presentations

Donate Now

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