Ketamine: Why Now? How? Where Do We Go from Here?

Tuesday, June 12, 2018, 2:00 pm EDT
Meet the Scientist - June 2018

Can the fast-acting antidepressant ketamine help people with PTSD? Scientists theorize that traumatic stress impairs the integrity of connections between nerve cells in the brain, leading to a variety of often debilitating problems, including those experienced by people with PTSD. Dr. Krystal explores the possibility of restoring damaged neural connections to provide relief for patients.

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Presented by 
John H. Krystal, M.D.
John H. Krystal, M.D.
Yale University School of Medicine

Robert L. McNeil, Jr. Professor of Translational Research and Professor of Psychiatry and of Neuroscience

Chair, Department of Psychiatry,

Chief of Psychiatry, Yale-New Haven Hospital

Director: NIAAA Center for the Translational Neuroscience of Alcoholism

Director, Clinical Neuroscience Division, VA National Center for PTSD

Scientific Council Member (Joined 2003)

2006, 2000 Distinguished Investigator Grant

1997 Independent Investigator Grant

Dr. Krystal is an expert on the neurobiology and treatment of schizophrenia, post-traumatic stress disorder, and alcoholism. In these areas, he has linked experimental psychopharmacology, neuroimaging, and genetics to identify disturbances in the function of brain circuits, particularly those involving glutamate and GABA that might be targeted in the development of new treatments. He developed the use of ketamine as a probe of glutamate receptor function in brain and behavior disorders. This work contributed to the development of mGluR2/3 agonist treatments for schizophrenia and riluzole and NMDA receptor antagonist treatments for depression and alcoholism.

President of the American College of Neuropsychopharmacology, Dr. Krystal has completed residency at Yale.

Moderated by 
Jeffrey Borenstein, M.D.
Brain & Behavior Research Foundation

President and CEO

Jeffrey Borenstein, M.D., serves as the President & CEO of the Brain & Behavior Research Foundation, the largest private funder of mental health research grants. Dr. Borenstein developed the public television program Healthy Minds and serves as host of the series. The program, which is broadcast nationwide, focuses on topics in psychiatry in order to educate the public, reduce stigma and offer a message of hope. Dr. Borenstein also serves as Editor-in-Chief of Psychiatric News, the newspaper of the American Psychiatric Association and as an Associate Clinical Professor of Psychiatry at Columbia University College of Physicians and Surgeons.