People with Bipolar Spectrum Disorders (BSDs) vary considerably in their clinical symptoms, a fact that contributes to the difficulty of developing new treatments. We need systems to measure how individuals with BSDs change over time and in different contexts. This talk will explain Dr. Sperry’s efforts to identify and implement ways to capture such heterogeneity and better predict illness course, treatment response, and healthcare utilization—the basis of future precision-medicine approaches to treatment. Dr. Sperry will discuss the results of a BBRF-funded study focused on characterizing intraindividual dynamics of mood, leveraging a rare cohort of patients with BSDs who were followed intensively over a 10-year period.
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