Decades of family and twin studies have established that substance use disorders have a familial and heritable component. With the advent of genome-wide association studies, our understanding of the genetic factors influencing substance use and misuse has progressed tremendously; hundreds of locations in the human genome have now been implicated in different aspects of substance use, and the list is expanding each year. Many of these DNA risk variations are shared across other psychiatric and other health disorders, a finding that suggests new ways of defining and potentially treating substance use disorders. This webinar will discuss these findings and some of the key advances that have made them possible, as well as new avenues of research that promise to shed new light on the biology of substance use disorders.
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