When Medicine is Not Enough for Schizophrenia and Psychosis

Tuesday, July 12, 2022, 2:00 pm EDT
Meet the Scientist - July 2022

Many individuals experience continued symptoms for Schizophrenia and Psychosis despite the best medication treatments available. What are some of the therapy approaches that can help when medicine is not enough? How do these approaches work?

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Presented by 
Dawn I. Velligan, Ph.D.
Dawn I. Velligan, Ph.D.

Director, Division of Community Recovery, Research and Training

Henry B. Dielmann Chair, Department of Psychiatry

University of Texas Health Science Center in San Antonio

2016 Distinguished Investigator Grant

2002 Independent Investigator Grant

1997 Young Investigator Grant

Dawn I. Velligan, Ph.D., of the University of Texas Health Science Center at San Antonio, will look for new biomarkers that are associated with particularly severe cases of schizophrenia. These markers will be used to assess a new treatment, known as the MOtiVation and Engagement (MOVE) Program. The method builds on existing therapies with comprehensive, home-based, multi-modal approaches, and results have been promising so far. Dr. Velligan will focus on inflammatory markers as potential biomarkers. He will examine the relationship between the amount of inflammatory markers circulating in the blood of patients and the severity of their negative symptoms. Dr. Velligan will also assess the impact of MOVE on levels of these molecules. This work has the potential to uncover novel biomarkers associated with the negative symptoms of schizophrenia, which may offer a path to more targeted, improved treatments.

Moderated by 
Jeffrey Borenstein, M.D.
Brain & Behavior Research Foundation

President and CEO

Jeffrey Borenstein, M.D., serves as the President & CEO of the Brain & Behavior Research Foundation, the largest private funder of mental health research grants. Dr. Borenstein developed the Emmy Award-nominated public television program “Healthy Minds,” and serves as host of the series. The program, which is broadcast nationwide, focuses on topics in psychiatry in order to educate the public, reduce stigma and offer a message of hope. Dr. Borenstein also serves as Editor-in-Chief of Psychiatric News, the newspaper of the American Psychiatric Association and as an Associate Clinical Professor of Psychiatry at Columbia University College of Physicians and Surgeons.