25 Years of Breakthroughs

25 Years of Breakthroughs

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Children born to older fathers have a higher risk of developing mental illnesses such as schizophrenia and autism spectrum disorders. Now, a new study suggests that age-related genetic mutations accumulated in the fathers’ genomes are unlikely to explain much of this increased risk.

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Fast-Acting Antidepressant Restores Ability to Experience Pleasure in People with Bipolar Disorder

Dr. Zarate and colleagues gave a single dose of ketamine to 36 treatment-resistant patients with bipolar disorder.

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Brain Plasticity

In 2013, NARSAD Grantee Kirsty Spalding, Ph.D., and team at the Karolinska Institutet in Stockholm, Sweden, used an innovative methodology to identify the “birth date” of neurons in deceased human brains.

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Treating Inflammation May Improve Resistant Depression

Foundation Grantee Andrew Miller, M.D., is the senior author of a study that demonstrates improvements in symptoms of depression in patients with high inflammation levels.

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Hongjun Song, Ph.D., of the Johns Hopkins School of Medicine, is intrigued about niches in a brain structure called the hippocampus where stem cells live and can give rise to new neurons, a process called neurogenesis. With the support of a 2008 NARSAD Independent Investigator Grant, Dr.

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