ketamine

Direct Evidence of Ketamine’s Antidepressant Action in Imaging Study of Excitatory Neuronal Receptors
A team of researchers has published results of experiments in patients with treatment-resistant depression that provides direct evidence of at least one important mechanism through which ketamine… Read More
Researchers Trace How Ketamine Acts on Specific Brain Circuits and Synapses to Relieve Anhedonia
Researchers have published a highly detailed account of a mechanism through which ketamine, a rapid-acting antidepressant, alters plasticity, or the strength of connections between neurons, and in so… Read More
Novel Target in Dopamine Neurons is Basis of Potential New Therapeutic Approach for Treatment-Resistant Depression
Even with the development and FDA approval in recent years of the first rapid-acting antidepressant medicines—to which more than 90 BBRF grants have contributed—the search for novel depression… Read More
Nitrous Oxide (“Laughing Gas”) May Have Rapid-Acting Anti-Suicidal Effects
Newly reported analysis of the results of three small clinical trials indicates that the gas nitrous oxide (N₂O) may have rapid-acting anti-suicidal effects. Nitrous oxide is often called laughing… Read More
Trial Finds Ketamine and ECT About Equally Effective for Most Patients with Resistant Major Depression
In a clinical trial involving hundreds of patients, ketamine has been found to be about as effective as electroconvulsive therapy (ECT) for treatment of major depressive disorder that has not… Read More