Trauma

Brain Signature Predicts Who Benefits from Exposure Therapy

In people with Post-Traumatic Stress Disorder (PTSD), certain brain activity patterns, in response to emotional cues, can predict who will benefit from exposure therapy, researchers report in a study published

Cognitive Impairments are Early Symptoms of Psychotic Disorders

Patients with traumatic brain injury (TBI) showed improvement in attention, memory, and executive functioning when treated with a combination of metacognitive rehabilitation and pharmaceuticals, according to a new study.

Adolescents With Bipolar Disorder Not More Likely to be Overweight

The prevalence of excess weight and obesity is similar among adolescents with and without bipolar disorder, according to a new analysis of nationally collected survey data.

Sleep Disturbances Linked to Symptom Severity Among Those At High Risk for Psychotic Disorders

Athletes with a history of concussions have signs of above-average inflammation in their brains that can be detected with a PET scan, according to a new study of active and recently retired NFL players.

TAKEAWAY: Researchers have identified a molecular pathway in a specific neural connection in the brain that is disrupted in patients with 22q11 deletion syndrome, a genetic error that is associated with schizophrenia. The pathway, which relies on a microRNA called miR-338-3p, is involved in neural communication between regions of the brain that are likely involved in auditory hallucinations and psychosis, suggesting it may be a potential drug target for alternative therapeutic strategies

In people with post-traumatic stress disorder (PTSD), fear-associated brain circuits overreact to cues that are similar to—but not the same as—features of a past traumatic experience.

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