rapid-acting antidepressants

Positive Results in Trial Testing ‘Laughing Gas’ in Severely Depressed Treatment-Resistant Patients
Newly reported results of a small phase 2 clinical trial indicate the potential utility of using nitrous oxide treatments in patients with severe major depression that has not responded to other… Read More
Remarkable Results in a Preliminary Clinical Test of a Rapid-Acting Antidepressant Treatment
Imagine a new treatment for people with major depression who have not responded to existing treatments—one that acts rapidly and helps a much larger fraction of such patients than any current… Read More
In a Surprising Clinical Trial, Ketamine’s Antidepressant Effects Lasted Longer
Carefully designed, exquisitely controlled experiments sometimes don't produce the result predicted in advance—the research “hypothesis” that is the starting point for a program of research. That is… Read More
Over Two Decades, 90 BBRF Grants Helped Build a Scientific Foundation for the First Rapid-Acting Antidepressants
In the spring of 2019, The Food and Drug Administration granted approval for two breakthrough medicines that act rapidly to alleviate symptoms of major depression. Esketamine, a drug administered via… Read More
Study: Ketamine Restores Neural Connection Points Lost in Stress & Depression
Researchers led by 2013 BBRF Young Investigator Conor Liston, M.D., Ph.D., have just reported a surprising finding about the drug ketamine, concerning the way it acts on the brain. Approved many… Read More