Dr. Steve Ramirez is revealing where memories “live” in the brain, and explores how traumatic memories might be therapeutically modified.
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A Q&A with Dr. Kimberly Carpenter of Duke University, who has conducted important research on preschoolers with overly sensitive senses—children who are intensely bothered by stimuli such as loud or high-pitched sounds, or the sensation of clothing rubbing on the skin. Her research has shown that these children are at greater risk for developing an anxiety disorder by school age. She also discusses sensory oversensitivity and autism spectrum disorder.
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Our PATHWAYS TO THE FUTURE story is about an unconventional approach to developing new psychiatric drugs. Based on an initiative by the National Institute of Mental Health, it’s called “Fast-Fail” and is designed to weed out the weakest drug candidates early in the process, to save time and money. In its first comprehensive test, a team led by two BBRF grantees and including 11 other BBRF grantees, Scientific Council members and prize winners, demonstrated the approach using a potential drug to treat anhedonia—the inability to experience or seek pleasure—which is seen in a number of psychiatric disorders including depression, anxiety, and PTSD.
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Q&A with Dilip Jeste, M.D., on the role of wisdom in dealing with what he has called “an epidemic of loneliness and despair” in America.
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