Brain Matters
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Treatment–Resistant Depression

An important discovery has been made at the University of Pittsburgh. It raises the prospect that there may be an entirely new way of relieving major depression in people who repeatedly have failed to respond to existing treatments—people at elevated risk for suicide whose lives are often unrelentingly dark and full of anguish.

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Doctors Without Borders/Médecins Sans Frontières

The Pardes Humanitarian Prize in Mental Health was established in 2014, and is awarded annually to recognize individuals or organizations that are making a profound and lasting impact in advancing the understanding of mental health and improving the lives of people suffering from mental illness.

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Pathways to the Future

On Friday, July 28th at the Metropolitan Club New York, the Foundation celebrated 30 years of awarding research grants, honored our Scientific Council, and announced the winners of our annual Klerman & Freedman Prizes, which recognize excep

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Diagnosing Early-Onset Depression in Young Children

There was a longstanding belief that pre-pubescent children were too developmentally and cognitively immature to experience the core aspects of depression. In the mid-1980s research studies disputed those claims. By the late ‘80s, it was widely accepted that children ages six and older could experience clinical depression. Subsequently, treatment studies looked at various forms of psychotherapy and psychopharmacology for that age group. Recent studies, including ours at Washington University, have extended that story down to age three.

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Why We Need More Conversation About Borderline Personality Disorder

A disorder that affects nearly two percent of the population and 10 percent of psychiatric patients is strikingly absent from common conversation.

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